ABSTRACT
ObjectiveToexplorefeasibilityofinterpleuralblockviacostodiaphragmaticrecessesfortreating functionaldyspepsia(FD).Methods 88FDpatientsincludingthreesubtype:postprandialdistresssyndrome(PDS 24cases),epigastric pain syndrome(EPS 28 cases)and PDS overlapping EPS( 36 cases)were divided into two groups randomly according to FD subtype:treatment group and control group.The control group were treated with paroxetine, metoclopramide and omeprazole,PO,8 weeks per course of treatment;The treatment group were treated by interplural blocks via costodiaphragmatic recesses ( CDR ) on the basis of treatment of control group, sterile syringe needles of 20mL were inserted vertically by the methods of resistance lossing into CDR,the widest position of interplural space through superior borders of the ninth ribs of the affected sides in midaxillary lines.Weekly injections of 20 mL of anti-phlogistic and analgetic solution were given over a four-week period.VAS,SCL-90 and degree of postprandial distress were evaluated before treatment,at 1 week and 6 months after treatment.Results The patients of the two groups a-chieved pain,depression and anxiety and postprandial distress relief obviously after treatment,VAS and SCL-90 de-creased significantly.Before the treatment,the VAS scores of the two group were (7.66 ±1.14) points,(7.57 ± 1.18)points,respectively,which after the treatment were (1.13 ±0.33) points,(3.22 ±0.66) points;Before the treatment,the SCL-90 scores of the two group were (173.56 ±10.21) points, (174.50 ±11.18) points,respectively, which after the treatment were (106.52 ±9.91) points,(106.38 ±10.12) points.There were statistically significant differences between pretreatment and posttreament in the two groups(all P<0.05),and the treatment group was bet-ter and lasted longer than that of control group(all P<0.05).Conclusion Interplural block via CDRs for treating FD is a feasible,simple,safe,effective approach and can be provided on an outpatient basis.